Elimination versus ring opening: A convergent route to alkylidene- cyclobutanes

Julien Brioche 1 Michal Michalak 1 Béatrice Quiclet-Sire 1 Samir Zard 1
1 DCSO - Laboratoire de synthèse organique
Abstract : Functionalized alkylidene-cyclobutanes have been prepared from 2-fluoropyridinyl-6-oxy precursors derived from vinyl cyclobutanols by a radical addition-elimination process. A wide range of functional groups is tolerated, and the alkylidene-cyclobutanes can be further elaborated into cyclopentanones. The limitation of this approach resides in the competition with opening of the cyclobutane ring. © 2011 American Chemical Society.
Document type :
Journal articles
Complete list of metadatas
https://hal-polytechnique.archives-ouvertes.fr/hal-00950020
Contributor : Denis Roura <>
Submitted on : Wednesday, February 26, 2014 - 9:43:26 AM
Last modification on : Thursday, February 7, 2019 - 5:16:41 PM

Identifiers

Collections

X-DCSO | X | PARISTECH | INC-CNRS | X-DEP-CHIM

Citation

Julien Brioche, Michal Michalak, Béatrice Quiclet-Sire, Samir Zard. Elimination versus ring opening: A convergent route to alkylidene- cyclobutanes. Organic Letters, American Chemical Society, 2011, 13 (23), pp.6296-6299. ⟨10.1021/ol202798r⟩. ⟨hal-00950020⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

274

Contact

support.ccsd.cnrs.fr
hal.support@ccsd.cnrs.fr
Logo CCSD