Multicomponent synthesis of fused benzimidazolopiperazines

Laurent El Kaim 1 Laurence Grimaud 1 Srinivas Reddy Purumandla 1
1 DCSO - Laboratoire de synthèse organique
Abstract : We present a novel protocol for the efficient synthesis of fused benzimidazolo piperazines starting from a four-component Ugi-Smiles reaction and a subsequent three-step cascade involving an acid-catalyzed cyclization, an intramolecular reductive cyclization, and an oxidation. © 2011 American Chemical Society.
Document type :
Journal articles
Complete list of metadatas
https://hal-polytechnique.archives-ouvertes.fr/hal-00951229
Contributor : Denis Roura <>
Submitted on : Wednesday, February 26, 2014 - 9:21:11 PM
Last modification on : Thursday, February 7, 2019 - 5:10:36 PM

Identifiers

Collections

X-DCSO | X | PARISTECH | INC-CNRS | X-DEP-CHIM

Citation

Laurent El Kaim, Laurence Grimaud, Srinivas Reddy Purumandla. Multicomponent synthesis of fused benzimidazolopiperazines. Journal of Organic Chemistry, American Chemical Society, 2011, 76 (11), pp.4728-4733. ⟨10.1021/jo200397m⟩. ⟨hal-00951229⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

192

Contact

support.ccsd.cnrs.fr
hal.support@ccsd.cnrs.fr
Logo CCSD