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Journal Articles Journal of Organic Chemistry Year : 2011

Multicomponent synthesis of fused benzimidazolopiperazines

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Abstract

We present a novel protocol for the efficient synthesis of fused benzimidazolo piperazines starting from a four-component Ugi-Smiles reaction and a subsequent three-step cascade involving an acid-catalyzed cyclization, an intramolecular reductive cyclization, and an oxidation. © 2011 American Chemical Society.
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hal-00951229 , version 1 (26-02-2014)

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Laurent El Kaim, Laurence Grimaud, Srinivas Reddy Purumandla. Multicomponent synthesis of fused benzimidazolopiperazines. Journal of Organic Chemistry, 2011, 76 (11), pp.4728-4733. ⟨10.1021/jo200397m⟩. ⟨hal-00951229⟩
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