 |
École polytechnique Open archive |  |
 |
Journal articles
Tin-free radical cyclizations for the synthesis of 7-azaoxindoles, 7-azaindolines, tetrahydro[1,8]naphthyridines, and tetrahydro-5H-pyrido[2,3-b] azepin-8-ones
Abstract : (Chemical Equation Presented) Compounds containing a pyridine nucleus fused to a saturated nitrogen-containing ring, including 7-azaoxindoles, 7-azaindolines, tetrahydro[1,8]naphthyridines, and tetrahydro-5H-pyrido[2,3-b] azepin-8-ones, were prepared in good yield starting from various 2,6-dichloropyridines. The method hinges on a free-radical xanthate-mediated cyclization or intermolecular addition/cyclization sequence for the construction of the new fused rings.
https://hal-polytechnique.archives-ouvertes.fr/hal-00954818
Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Monday, March 24, 2014 - 1:24:10 PM
Last modification on : Thursday, December 9, 2021 - 2:26:02 PM
Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Monday, March 24, 2014 - 1:24:10 PM
Last modification on : Thursday, December 9, 2021 - 2:26:02 PM