A practical variation on the Paal-Knorr pyrrole synthesis

Béatrice Quiclet-Sire; Leticia Quintero; Graciela Sanchez-Jimenez; Samir Zard

doi:10.1055/s-2003-36223

Journal articles

A practical variation on the Paal-Knorr pyrrole synthesis

Béatrice Quiclet-Sire ¹ Leticia Quintero ² Graciela Sanchez-Jimenez ¹ Samir Zard ^{1, *}

* Corresponding author

1 DCSO - Laboratoire de synthèse organique

2 Centro de Investigacion de la Facultad de Ciencias Quimicas

Abstract : The radical addition of a-xanthyl ketones to vinyl pivalate gives adducts that are synthetic equivalents of 1,4-ketoaldehydes; treatment with ammonia or primary amines leads to the corresponding pyrroles in high yield.

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A practical variation on the Paal-Knorr pyrrole synthesis

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A practical variation on the Paal-Knorr pyrrole synthesis

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