A new example of 1a-hydroxylation of drimanic terpenes through combined microbial and chemical processes

Gérard Aranda 1 L. Moreno 2 M. Cortés 2 T. Prangé 3 M. Maurs 4 R. Azerad 4
1 DCSO - Laboratoire de synthèse organique
2 Facultad De Química
3 Chimie Structurale Biomoléculaire
4 LCBPT - UMR 8601 - Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques
Abstract : Among various filamentous fungi, Aspergillus niger ATCC 9142 was the most efficient strain to convert confertifolin in high yield into its 3ß-hydroxy derivative, which was then chemically converted to 1a-hydroxy-, 1a,11a-dihydroxy- and 1a-acetoxy-11a-hydroxyconfertifolin, new compounds structurally related to bioactive natural products isolated from plants or marine sponges. © 2001 Elsevier Science Ltd.
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Tetrahedron, Elsevier, 2001, 57 (28), pp.6051-6056. 〈10.1016/s0040-4020(01)00595-6〉
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Soumis le : jeudi 13 mars 2014 - 21:34:25
Dernière modification le : jeudi 10 mai 2018 - 02:07:42

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Gérard Aranda, L. Moreno, M. Cortés, T. Prangé, M. Maurs, et al.. A new example of 1a-hydroxylation of drimanic terpenes through combined microbial and chemical processes. Tetrahedron, Elsevier, 2001, 57 (28), pp.6051-6056. 〈10.1016/s0040-4020(01)00595-6〉. 〈hal-00954868〉

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