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Investigating the Cell Membrane via Single Particle Tracking, Bayesian Inference and Hydrodynamic Force Application
Abstract : We investigate the potential felt by membrane receptors inside membrane microdomains via tracking of single receptors labelled with rare-earth doped luminescent nanoparticles and Bayesian inference analysis of the recorded trajectories. We demonstrated that the potential felt by peptidic toxin receptors confined in lipid rafts is well described by a second-order polynomial potential, possibly due to an inhomogeneous lipid and protein distribution [Türkcan et al., Biophys. J. 2012] In contrast, the potential experienced by transferrin receptors in cytoskeleton-delimited microdomains is localized at the border of the confinement domain.
https://hal-polytechnique.archives-ouvertes.fr/hal-01048723
Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Friday, July 25, 2014 - 11:30:08 AM
Last modification on : Wednesday, November 17, 2021 - 12:29:13 PM
Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Friday, July 25, 2014 - 11:30:08 AM
Last modification on : Wednesday, November 17, 2021 - 12:29:13 PM
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