Access to New Endoperoxide Derivatives by Electrochemical Oxidation of Substituted 3-Azabicyclo[4.1.0]hept-4-enes

Abstract : A series of substituted 3-azabicyclo[4.1.0]hept-4-ene derivatives were prepared and analysed by cyclic voltammetry. Preparative aerobic electrochemical oxidation reactions were then carried out. Three original endoperoxides were isolated, characterised and subjected to antimalarial and cytotoxicity activity assays.
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Submitted on : Monday, July 20, 2015 - 8:13:25 AM
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Frédérick Nuter, Abdou Khadre Djily Dimé, Cheng Chen, Lotfi Bounaadja, Elisabeth Mouray, et al.. Access to New Endoperoxide Derivatives by Electrochemical Oxidation of Substituted 3-Azabicyclo[4.1.0]hept-4-enes. Chemistry - A European Journal, Wiley-VCH Verlag, 2015, 21 (14), pp.5584-5593. ⟨10.1002/chem.201406138⟩. ⟨hal-01178411⟩

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