Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1 H -indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate

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Submitted on : Friday, April 6, 2018 - 2:36:11 PM
Last modification on : Tuesday, August 6, 2019 - 12:22:42 PM

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Stefano Crosignani, Patrick Bingham, Pauline Bottemanne, Hélène Cannelle, Sandra Cauwenberghs, et al.. Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1 H -indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate. Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (23), pp.9617 - 9629. ⟨10.1021/acs.jmedchem.7b00974⟩. ⟨hal-01760561⟩

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