Abstract : NH-aryl hydrazones derived from trifluoroacetaldehyde hemiacetal may be involved in efficient Mannich type reactions with formaldehydes and aromatic aldehydes. The resulting hydrazones are useful building blocks for the preparation of trifluoromethyl substituted heterocycles as shown by a straightforward preparation of 1,2-diazine derivatives under heating with β-ketoesters.
https://hal-polytechnique.archives-ouvertes.fr/hal-02095052
Contributor : Aurélien Arnoux
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Submitted on : Wednesday, April 10, 2019 - 10:53:41 AM
Last modification on : Wednesday, July 3, 2019 - 10:48:05 AM
