Modular Route to Azaindanes - Archive ouverte HAL Access content directly
Journal Articles Organic Letters Year : 2017

Modular Route to Azaindanes

(1) , (1)
1

Abstract

A convergent radical based route to azaindanes is described, relying on the degenerative addition transfer of various substituted S-(pyridylmethyl)-O-ethyl dithiocarbonates (xanthates) to functional alkenes followed by radical cyclization onto the pyridine ring activated by protonation with trifluoroacetic acid. In one case, a richly decorated cyclohepta[b]pyridine could be assembled swiftly by allowing the first adduct to N-phenylmaleimide to undergo addition to N-allylphthalimide prior to cyclization.
Not file

Dates and versions

hal-02095075 , version 1 (10-04-2019)

Licence

Copyright

Identifiers

Cite

Qi Huang, Samir Z. Zard. Modular Route to Azaindanes. Organic Letters, 2017, 19 (14), pp.3895-3898. ⟨10.1021/acs.orglett.7b01772⟩. ⟨hal-02095075⟩
17 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More