A flexible radical-based approach to tms-substituted propargyl alcohols and to 2,3-allenols

Zhi Li (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

The radical reaction of TMS-substituted xanthates with 2,2-dlchlorovlnyl ethyl sulfone afforded TMS-substltuted homodichlorovinyl compounds that can be transformed Into TMS-substituted propargyl alcohols. Various 2,3-allenols were efficiently prepared from the reaction of these TMS-substituted propargyl alcohols with TBAF. © 2009 American Chemical Society.

Domaines: Chimie organique

Zhi Li, Samir Z. Zard. A flexible radical-based approach to tms-substituted propargyl alcohols and to 2,3-allenols. Organic Letters, 2009, 11 (13), pp.2868-2871. ⟨10.1021/ol900739x⟩. ⟨hal-00951260⟩