Synthesis of substituted 4-arylpiperidin-2-ones by a 6-exo-trig radical cyclization

Xavier Vila (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

A series of 5-substituted-4-arylpiperidin-2-ones have been synthesized in a 4 step sequence involving a radical 6-exo-trig cyclization as the key step. © 2006 The Japan Institute of Heterocyclic Chemistry.

Xavier Vila, Samir Z. Zard. Synthesis of substituted 4-arylpiperidin-2-ones by a 6-exo-trig radical cyclization. Heterocycles, 2006, 70 (1), pp.45-50. ⟨10.3987/COM-06-S(W)7⟩. ⟨hal-00954782⟩