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Access to 4-substituted 3,4-dihydroquinolin-2(1H)-ones by an unusual radical cyclisation of a secondary amide

Grégori Binot 1 Samir Z. Zard 1 
1 DCSO - Laboratoire de synthèse organique
Abstract : A novel route to 3,4-dihydroquinolin-2(1H)-ones involving two radical addition steps is reported, starting from readily accessible xanthates and N-aryl-3-butenamides. © 2005 Elsevier Ltd. All rights reserved.
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Submitted on : Monday, March 24, 2014 - 5:19:49 PM
Last modification on : Thursday, December 9, 2021 - 2:26:02 PM

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Grégori Binot, Samir Z. Zard. Access to 4-substituted 3,4-dihydroquinolin-2(1H)-ones by an unusual radical cyclisation of a secondary amide. Tetrahedron Letters, Elsevier, 2005, 46 (44), pp.7503-7506. ⟨10.1016/j.tetlet.2005.09.006⟩. ⟨hal-00954803⟩

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