Access to 4-substituted 3,4-dihydroquinolin-2(1H)-ones by an unusual radical cyclisation of a secondary amide

Grégori Binot (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

A novel route to 3,4-dihydroquinolin-2(1H)-ones involving two radical addition steps is reported, starting from readily accessible xanthates and N-aryl-3-butenamides. © 2005 Elsevier Ltd. All rights reserved.

Grégori Binot, Samir Z. Zard. Access to 4-substituted 3,4-dihydroquinolin-2(1H)-ones by an unusual radical cyclisation of a secondary amide. Tetrahedron Letters, 2005, 46 (44), pp.7503-7506. ⟨10.1016/j.tetlet.2005.09.006⟩. ⟨hal-00954803⟩