Short cuts toward forskolin synthesis: A pentacyclic approach

Massoumé Leclaire 1, * Raymond Levet 1 Franck Ferreira 1 Paul-Henri Ducrot 2 Jean-Yves Lallemand 3 Louis Ricard 3
* Auteur correspondant
1 DCSO - Laboratoire de synthèse organique
2 Unité de phytopharmacie et médiateurs chimiques
3 DCPH - Laboratoire Hétéroéléments et Coordination
Abstract : A practical synthetic route for the preparation of forskolin intermediate 20 is described. Previously reported lactone 3 was converted to 20 through intermediate 16. The main feature of this work lies in the formation and the cleavage of a tetracyclic intermediate for the stereochemical control in the formation of the tricyclic core of forskolin.
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Article dans une revue
Chemical Communications, Royal Society of Chemistry, 2000, pp.1737-1738. 〈10.1039/B004515M〉
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https://hal-polytechnique.archives-ouvertes.fr/hal-00954908
Contributeur : Denis Roura <>
Soumis le : mardi 11 mars 2014 - 13:10:39
Dernière modification le : jeudi 10 mai 2018 - 02:07:44

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Massoumé Leclaire, Raymond Levet, Franck Ferreira, Paul-Henri Ducrot, Jean-Yves Lallemand, et al.. Short cuts toward forskolin synthesis: A pentacyclic approach. Chemical Communications, Royal Society of Chemistry, 2000, pp.1737-1738. 〈10.1039/B004515M〉. 〈hal-00954908〉

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