Short cuts toward forskolin synthesis: A pentacyclic approach

Massoumé Leclaire 1, * Raymond Levet 1 Franck Ferreira 1 Paul-Henri Ducrot 2 Jean-Yves Lallemand 3 Louis Ricard 3
* Corresponding author
1 DCSO - Laboratoire de synthèse organique
2 Unité de phytopharmacie et médiateurs chimiques
3 DCPH - Laboratoire Hétéroéléments et Coordination
Abstract : A practical synthetic route for the preparation of forskolin intermediate 20 is described. Previously reported lactone 3 was converted to 20 through intermediate 16. The main feature of this work lies in the formation and the cleavage of a tetracyclic intermediate for the stereochemical control in the formation of the tricyclic core of forskolin.
Document type :
Journal articles
Complete list of metadatas
https://hal-polytechnique.archives-ouvertes.fr/hal-00954908
Contributor : Denis Roura <>
Submitted on : Tuesday, March 11, 2014 - 1:10:39 PM
Last modification on : Wednesday, March 20, 2019 - 12:12:31 PM

Identifiers

Collections

CNRS | X-DCSO | X | X-DCPH | PARISTECH | INC-CNRS | INRA | X-DEP-CHIM

Citation

Massoumé Leclaire, Raymond Levet, Franck Ferreira, Paul-Henri Ducrot, Jean-Yves Lallemand, et al.. Short cuts toward forskolin synthesis: A pentacyclic approach. Chemical Communications, Royal Society of Chemistry, 2000, pp.1737-1738. ⟨10.1039/B004515M⟩. ⟨hal-00954908⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

228

Contact

Informations

CCSD