Short cuts toward forskolin synthesis: A pentacyclic approach

Abstract : A practical synthetic route for the preparation of forskolin intermediate 20 is described. Previously reported lactone 3 was converted to 20 through intermediate 16. The main feature of this work lies in the formation and the cleavage of a tetracyclic intermediate for the stereochemical control in the formation of the tricyclic core of forskolin.
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Chemical Communications, Royal Society of Chemistry, 2000, pp.1737-1738. 〈10.1039/B004515M〉
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Soumis le : mardi 11 mars 2014 - 13:10:39
Dernière modification le : jeudi 10 mai 2018 - 02:07:44

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Massoumé Leclaire, Raymond Levet, Franck Ferreira, Paul-Henri Ducrot, Jean-Yves Lallemand, et al.. Short cuts toward forskolin synthesis: A pentacyclic approach. Chemical Communications, Royal Society of Chemistry, 2000, pp.1737-1738. 〈10.1039/B004515M〉. 〈hal-00954908〉

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